How does a BiTE antibody work?

T cells are prime enemies of cancer cells Cytotoxic T cells (top) are key players of the body's immune defense. There are billions of them continuously patrolling the body detecting and eliminating malfunctioning cells (bottom). Their highly toxic payload of cell death-inducing enzymes (called granzymes) and a pore-forming protein (perforin) make them one of the most potent killer cells of the human immune system. |